A rare case of field cancerization of oral squamous cell cancer along with brain metastasis: Case report with review of literature

Oral cancer is any malignant neoplasm of buccal mucosa, tongue, lip, floor of mouth, gingival or palate. Oral cancer is the 6th most common cancer of the world and 3rd most common in South-Central Asia. In Asian countries like India, buccal mucosa is the most common site of oral cancer. Head and neck cancer patients are at high risk of developing Second primary tumor arising from same dysplastic mucosal field. Metastasis of OSCC occurs at a reported rate of 4% to 26%. Most distant metastasis from OSCC is reported to occur in liver, lungs and bone. Although brain metastasis is commonly seen in lung cancers, breast cancers and melanomas, it is a rare finding in OSCC, accounting for as low as 1% of all reported cases.