The history of discovery of full closed cycle of proton conductance inside human body

Our first imagination was that the evolution history of development of lifeprocesses in our planet during last billion year should build the full closed cycle of protons, with direct participation of this cycle have been formed more than 100 kg ATP during 24 hours and heat energy, enough to warm the human body until 36-37 Celsius degree, where protons have been recirculated, reutilized, making repeated circulation movement within concrete interval time. At first we had been succeeded to find the end 9-th stage of the full closed cycle of electron, proton conductance, which basic features may be described as entry of oxygen from lung, formation of HbO2, proton combine with hemaglobin (generation of HbH) which promotes the release of oxygen from hemaglobin, oxygen diffusion to all cells conditioning the release of proton, electron from food substrates in the 1-stage, also proton released from hemaglobin promotes uptake of oxygen by hemaglobin, which we named as 9-th stage of the full closed cycle. In this connection it was raised the question as which basic features should be bear the 8-th stage of the full closed cycle. After this, it was became clear that the 8-th stage of the full closed cycle had been distinguished by the diffusion of proton from mitochondrial matrix of all cells in the form of HCO3 as the protonated carbon dioxide, and metabolic water through plasma membrane of red blood cells with participation of aquaporin protein channels and by Na+/H+antiport mechanism, also entry of CO2 from all cells.