Community health workers (CHWs) are widely used to provide care for a broad range of health issues. The study is aimed to assess knowledge about health programs among community health workers. A sample of 240 health workers was randomly selected from health center at Ruhango district. Questionnaire method was used for data collection and analysis was done through frequency and percent. It has been observed from this study that majority of the health workers had possessed knowledge about timing of first ANC visit in first trimester (97%) and number of ANC visit required during pregnancy(83%),knowledge on providing counseling to women (>95%) on Intake of nutritive food ,proper rest, exercise ,checkup, etc during pregnancy. In this paper, an attempt has been made to assess the level of knowledge of community health workers, focusing on maternal health care and newborn health care