Safeguarding public health from mela-associated cholera outbreaks: evidence from a jhalawar district study

Aims and introduction: To investigate a recent outbreak of Vibrio cholerae during the Mela and inform evidence-based interventions and enhance preparedness efforts. Out of the various infectious diseases, Vibrio cholerae causes a severe diarrheal disease with potentially fatal consequences if left untreated. The emergence and spread of such outbreaks continue to pose a formidable challenge in densely populated areas and during mass gatherings such as religious festivals and pilgrimages. Through this study, we endeavor to contribute valuable insights into the epidemiology of cholera and advance our ability to anticipate, detect, and respond to such outbreaks. Materials and method: The study included 253 stool samples collected, transported, and processed according to protocol. The isolates obtained were further subjected to AST and antisera testing. Moreover, water samples from 35 water sources were also analyzed for the presence of pathogenic organisms. Results: Out of the total 253 stool samples received 227 were V.cholerae. Among patients, the most common age group was 16 to 30 years (84). Males were more infected (121). Conclusion: This study will provide valuable insights into the characteristics of the cholera outbreak at pilgrimages.