Role of computed tomography in diagnosis of neoplastic sinonasal diseases

Computed Tomography plays a major diagnostic role in evaluation of patients with neoplastic sinonasal diseases and determines the mode of management. The purpose of the present study is to assess the role of CT in diagnosis of neoplastic sinonasal diseases by correlating CT diagnosis with final histopathological diagnosis and evaluating the sensitivity and specificity of CT. This study was a retrospective hospital based study executed in the Department of Radiodiagnosis, Acharya Vinobha Bhave Rural hospital (AVBRH) attached to Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha. Study included 175 patients with symptomatic sinonasal diseases who were evaluated by 16 slice MDCT and final diagnosis was obtained. Out of 175 patients 38 had neoplastic histopathological diagnosis in ehich the findings were correlated with CT diagnosis. Then sensitivity and specificity of CT was evaluated. Statistical analysis was done by descriptive and inferential statistics using Test statistics (sensitivity, specificity, ppv, npv and accuracy) and Z test for single proportions (Z value > 1.96 is considered significant). Software used in the analysis was SPSS 17.0 version and graph pad prism 6.0 version and p < 0.05 is considered as level of significance. On correlating CT diagnosis with final diagnosis, Benign neoplasms had sensitivity of 95.24% and specificity of 99.35%, positive predictive value 95.24%, negative predictive value with 99.35% and accuracy of 98.86%. Malignant neoplasms had sensitivity of 88.89% and specificity of 99.36%, positive predictive value 94.12% and negative predictive value 98.73% with 98.29% accuracy. P value in all instances was < 0.05 i.e. <0.0001, indicating the significance of the findings.