Role of age of menarche and age of menopause in determining bone mineral density in post menopausal womenat sms medical college jaipur, rajasthan

Introduction: Reduction of bone density and development of osteoporosis in postmenopausal women is very commonly seen in India and causes significant morbidity. Many of these women were found to have age of menarche and age of menopause affecting the bone mineral density of postmenopausal women. derangements in lipid profiles especially serum cholesterol levels. AIMS AND Objectives: To find a correlation between age of menarche as well as age of menopause and Bone mineral density in post menopausal women. Material & Methods: The study was carried on matched cases and controls. The experimental group consisted of 55 females at postmenopausal age, in which by the DEXA method was diagnosed osteoporosis while the control group consisted of 55 females in a postmenopausal age but without diagnosed osteoporosis who served as controls. Age of menarche and age of menopause were determined in both cases and controls. Results: Most women achieved their menopause at 51-55 years of age in both the groups and majority amongst them achieved their menarche between 12-13 years. The mean age at menopause in Group Ⅰ women was 50.32±1.41 years and in Group Ⅱ was 49.67±1.36 years. The difference in menopausal age in both the groups was found to be statistically insignificant (p-value=0.865). The result was also not significantly associated with the age of achieving menarche(p value 0.060). CONCLUSION: No correlation was found between age of attaining menarche or menopause in this study however The sample is relatively small and not large enough to cause adequate study power to the results. Second, repeat measurement of lipids may be necessary for decreasing confounding factors such as diet on lipid profile