Multiple Sclerosis is an autoimmune and neurological disorder. The disease can be identified by some early signs and symptoms like numbness, confusion and many others. If neglected can lead to progressive development of disease where based on the stage the disease is classified into four stages. Pathology and pathogenesis of the disease is discussed. Certain drugs which are approved by FDA are used in treating MS. Other than these drugs few monoclonal antibodies are also used. Use of stem cells in treatment of MS is found to be successful in animal models. We mainly discuss about the treatment methods which are available in market and also of those under trials.