Anaphylaxis is a serious life- threatening allergic reaction and requires emergent diagnosis and treatment. The first – line pharmacological treatment in anaphylaxis is intramuscular adrenaline. Concurrent occurrence of acute coronary syndromes with hypersensitivity reactions is a rare but possible occurrence known as ‘Kounis Syndrome’. We report a case of a young healthy male with no significant risk factors for coronary artery disease developed ventricular tachycardia and myocardial infarction following therapeutic dose of intramuscular administration of adrenaline for an anaphylactic reaction to the ED.