CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Prognostic significance of macrophage migration inhibitory factor (mif) and tissue inhibitor of metalloproteinases-1(timp-1) in colorectal cancer (crc).

Author: 
Padmini Habbu, N. Ananthi and Abdul Kayyum shaikh
Subject Area: 
Life Sciences
Abstract: 

Background: Colorectal cancer (CRC) is the third most common epithelial malignancy in the world. Colorectal cancer develops slowly from removable precancerous lesions, detection of lesion can reduce the incidence and mortality of this malignancy. Hence the present study was under taken to relate the TIMP-1 and MIF protein analysis that are non- invasive, which may enable us to detect colorectal cancer quite early. Study design: Case control study. Aims and objectives: The present study included total 120 patients diagnosed with colorectal cancer. They categorized as- Group I – included 10 patients with disease dissemination (stage I-IV with recurrences); Group II – 110 patients with non dissemination (stage I-IV without recurrences) and Group III – 120 age and sex matched healthy controls. To rule out the risk of colorectal cancer CEA, Ca 19-9 and fecal hemoglobin were analyzed. Genetic and prognostic markers like, TIMP-1 and MIF protein were analyzed. All statistical analysis was performed by using SPSS software and expressed as mean ± standard deviation, p˂0.005 was considered as statistically significant. Correlations between the parameters were analyzed. Results: The concentration of CEA, Ca19-9, TIMP-1, MIF protein, level were significantly higher in patient group then in controls group (p˂0.005). A significant correlation between CEA and CA19-9, TIMP-1 and MIF were observed. Conclusions: In this study the level of TIMP-1 and MIF expression exhibits an upper moderate diagnostic value in CRC, and this result could offer new approaches in the diagnosis, prognosis and monitoring risk factors in colorectal cancer.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran