The incidence of ABO & Rh blood types varies among different population groups. The knowledge of the distribution of ABO & Rh blood groups is essential for effective management of blood banks, transfusion purposes, in population genetic study, transplantation, hemolytic disease & resolving certain medico–legal issues, of disputed parentage. Our aim was to determine the distribution of different blood groups in girl students in Y.C.W. M. Warananagar. A study was conducted at Zoology Department laboratory in Y.C.Warana Mahavidylaya over a period of two years – 2016 and 2017. During study, some Rh –ve girl students were found. The study of blood groups have a significant implication regarding the inventory management of blood bank, transfusion services and hemolytic disease. Present study concluded that most prevalent Rh negative blood groups are B & O while AB is rare blood group amongst the girl students in Y.C.Warana Mahavidylaya, Warananagar.