CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Potential plasmidic co-transfer, extended spectrum β--lactamase lineage and integron association in uropathogenic e. coli from an endemic region

Author: 
Sandip Kumar Mukherjee and Mandira Mukherjee
Subject Area: 
Life Sciences
Abstract: 

Resistance to extended-spectrum β-lactams was mediated by plasmidic extended-spectrum β-lactamases (ESBLs) and/or AmpC β–lactamases in uropathogenic E. coli (UPEC) a primary etiologic agent of urinary tract infections (UTI). Often the isolates were multidrug resistant harboring integrons and cause great hindrance in treatment. This study aims to identify genetic relatedness between plasmids and their correlation with β-lactamase resistant genes and integrons in nosocomial UPEC isolates. 29 drug resistant patterns were observed in 82 E. coli isolates after urine culture and biochemical detection. 33(45.8%) isolates were ESBL producers and 39 (54.2%) resistant to ESBL production. The former showed lowest resistance (3%, 24.2%) than the latter (43.6%, 35.9%) group to meropenem and nitofurantoin respectively. Conjugal transfer of plasmids was successful for 52 isolates. blaTEM was present in all transconjugants, alone or in combination with other β-lactamases and integrons. Mantel test revealed significant correlation (Rxy=0.997, p <0.0001) between plasmids, β-lactamase genes and integrons. Therefore this study demonstrated that flow of genetic information was due to mobile genetic elements instead of genetic recombination between plasmid pairs. Furthermore awareness, detection and distribution of resistant determinants were an absolute necessary for designing therapeutics for optimal patient care.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran