Digera muricata (L.) Mart. Leaves were selected to screen pharmacognostic and phytochemical studies. Plant material was collected from farmlands in Coimbatore district, Tamilnadu, India. Digera muricata (L.) Mart. is a well-known leafy vegetable and also a medicinal plant, which has been valued in ancient system of medicine. The leaf extracts of various solvents were subjected to organoleptic, fluorescence analysis, physicochemical analysis and preliminary phytochemical screening. The study contributes to the development of standardization parameters of herbal drugs used in our system of medicine