Oral cancer profile among patients who underwent oral biopsy in a tertiary referral centre in central Kerala India

Oral cavity is one of the commonest site for cancer in our population due to a high prevalence of tobacco use in the country. Aim: The aim of this study was to retrospectively assess the oral cancer profile among patients who underwent biopsy in a tertiary centre in Central Kerala and there by implement the preventive measures for controlling it. Materials and Methods: This retrospective study was conducted by analyzing the histopathological records in the Department of Oral and Maxillofacial Surgery, Government Dental College Kottayam from June 2008 to May 2014. Results: The study showed that among 1270 patients who underwent biopsy as a part of the diagnostic procedures during the study period, 570 (44.8%) patients were diagnosed as having dysplasia, premalignant and malignant lesions .Out of this, 361 patients were diagnosed with oral squamous cell carcinoma. There was an increased predilection of oral cancer among males and the predominant age group affected was between 61-70 years of age followed by 30-40 year age group. Buccal mucosa was the most common site accounting for 42.6% of the total cases. The most prevalent histopathological pattern was moderately differentiated squamous cell carcinoma. Statistically significant association was found between age group and histopathological grading, sub site and histopathological grading with p value <0.005. Conclusion: The increased prevalence and younger age group involvement of oral SCC in the study suggests that preventive measures should be implemented in our society at the earliest.The data found in the study can be used to make public awareness of the harmful effects tobacco and alcohol.