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Novel propenones bearing napthyl moiety as potent anti-malarial agents: Anti-tubercular screening activity and their synthesis and characterization

Author:

Chandraprabha V.J., Jagadeesh Prasad, D. Gayathri, B. H. and Prashantha Naik

Subject Area:

Physical Sciences and Engineering

Abstract:

Synthesis of novel propenones (2E)-1-(C)-3-(6-methoxynaphthalen-2-yl) prop-2-en-1-one (3) by the condensation reaction. The new target compounds were analyzed for their structures using FT-IR,1H-NMR, 13C-NMR and LC-Mass further these newly synthesized compounds were screened for their anti-TB and anti-malarial agents and the results of each such studies of these synthesized compounds revealed to possess excellent activity.

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