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Nitazoxanide: antiviral properties relevant to current global situation
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Life Sciences
Abstract:
Nitazoxanide is a broad-spectrum, orally active anti-infective initially developed for the treatment of protozoal disease. However, nitazoxanide and its active metabolite, tizoxanide, have demonstrated antiviral activity against a variety of viruses in preclinical and clinical settings. This review of the literature aims to present the pharmacological profile of nitazoxanide, mechanisms of antiviral action, and its demonstrated and potential antiviral applicability.
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