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Isolated immunoglobulin m deficiency presenting as progressive disseminated Histoplasmosis
Subject Area:
Health Sciences
Abstract:
Disseminated histoplasmosis is a very severe and often fatal opportunistic infection mostly seen in immunocompromised hosts and rarely in immunocompetent individuals. We report here a rare case of 13 year old male misdiagnosed as pulmonary tuberculosis and hodgkin’s lymphoma before eventually being diagnosed as histoplasmosis with an underlying isolated IgM deficiency to increase awareness of the clinical spectrum of disseminated histoplasmosis and its similarity to other infections and malignancies to encourage early diagnosis so that diagnostic and therapeutic pitfalls can be avoided to improve eventual outcome of the disease.
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