Intramuscular myxomas are benign mesenchymal tumours. They are commonly found in the atrial muscle. A search of the literature reveals a small scattering of reported cases in the gluteal region. However gluteal myxoma presenting as sciatica like symptoms are very rarely reported. We present a case of a hypothyroid middle aged female who had complaints of sciatica with a noticeable left buttock mass and was treated successfully with surgical excision.