Identification of Bioactive Secondary Metabolites from Marine Sponge Aurora globostellata by Hyphenated Analytical Methods

Two- third of the earth’s surface is covered by water especially marine water which provides rich sources of flora and fauna. The marine environment which contains a vast array of organisms with unique biological properties is one of the most underutilized biological resources. There is an ever increasing demand for new lead compounds in the pharmaceutical industry and this has led scientists to search for natural bioactive products. Among various marine species the Sponges (Porifera) are said to possess higher cytotoxic molecules as the secondary metabolites in them. These metabolites are produced by the Sponges and they create surface around them to defend themselves from predators. There is high number of available drugs for cancer, but still there is a growing need to develop more specific compounds for treatment. This study is focused on Aurora globostellata its collection, taxonomic identification, extraction, phytochemical analysis, and identification of compounds through GC-HRMS and HR-LCMS. The results obtained from analysis were found to contain higher number of anticancerous compounds, which can be used as a lead molecule for various cancer therapies. These drugs from natural sources can overcome the commercial drugs and can be used for the treatment of cancer.