Evaluation of bone healing and ridge preservation in mandibular and maxillary extraction socket following bone grafting with platelet rich plasma and platelet rich fibrin - a clinical and radiological study

Introduction: Background and objectives: The purpose of this study was to compare the efficacy of demineralized freeze dried bone graft with platelet rich fibrin (PRF), and demineralized freeze dried bone graft with platelet rich plasma (PRP) and collagen membrane in healing of extraction socket of maxillary and mandibular anterior and posterior teeth. Materials and method: 60 extraction sites were selected and divided into group I and group II. Group I consisted of DFDBG and PRF and group II consist of DFDBG and PRP along with collagen membrane. Each group comprising of thirty extraction sites were subjected to one of the two modalities (DFDBF with PRF and DFDBG with PRP) of treatment for, maxillary and mandibular extraction socket. Post-operatively the patients were evaluated for bone healing, pain and swelling following extraction and bone grafting, and to evaluate the bone height, width and density radiographs were taken at interval of 1st month, 3rd month and 6th month. Results: Results did show statistical differences (p>0.05) for parameters like bone height, width and density with group I, when compared with group II. Radiographically Bone height and Bone density was significantly higher with DFDBG and PRF group when compared with DFDBG and PRP group. Clinically here was no difference in terms of soft tissue healing with both the groups. Interpretation and Conclusion: Our study suggested that even though both modalities used in this study were effective for grafting extraction sockets, DFDBG and PRF group proved to be better in terms of bone height, width and density postoperatively. We conclude that the overall summation of the results of the study showed that DFDBG and PRF seams to offer better significant results both clinically and radiographically than DFDBG and PRP in ridge preservation of maxillary and mandibular extraction sockets.