Effects of different concentrations of zinc and arsenic on germination, root and shoot growth, dry weight of root and shoot and changes in content of total chlorophyll, carotenoids, total sugar and protein of Physalis minima L. was studied. The lower concentration of zinc has beneficial effect but application of higher level of zinc has an adverse effect. Arsenic reduced the percentage of germination, root and shoot length and dry weight of root and shoot. Total chlorophyll, carotenoids, sugar and protein were also affected by arsenic and their contents were decreased.