Comparative study of low dose v/s standard dose regime of Magnesium sulphate (MgSO4) in management of Eclampsia

This study is to compare the low dose with standard Pritchard's regime for controlling convulsion in patients of eclampsia. In this hospital based prospective study, cases presenting with classical features of eclampsia (beyond 20 weeks of pregnancy and upto 7 days postpartum) and meeting inclusion criteria's were included as per confounding of both the groups i.e. Group-A and Group-B. 25 cases were given low dose Magnesium Sulphate (Study Group; Group-A) and 25 cases were given standard dose regimen (Control Group; Group-B) after informed and written consent. In our study after statistical analysis we concluded that Magnesium Sulphate is required for controlling the convulsions of eclampsia but low dose regime is very simple to administer and easy to monitor and is as effective as Pritchard's regime with minimal possible side effects and better perinatal outcome.