Chronicity of hiv infection and oral health: unveiling emerging perspectives

The quest for HIV eradication has seen significant progress with the advent of highly active antiretroviral therapy (HAART), transforming HIV infection from a life-threatening condition to a manageable chronic disease. Recent research endeavors have focused on understanding HIV pathogenesis, exploring novel therapeutic strategies, and addressing challenges associated with long-term treatment and eradication efforts. Clinical interventions aimed at curing HIV infection have been explored extensively, with trials testing various immune interventions and diagnostic systems to target latent viral reservoirs and improve clinical monitoring. While improvements in virological and immunological outcomes offer hope for increased life expectancy among PLHIV on ART, challenges remain in achieving parity with the general population. Timely diagnosis and treatment have been shown to enhance life expectancy, but the presence of comorbidities not linked to AIDS poses a significant risk, particularly among women. Efforts to eradicate HIV also encompass infections among PLHIV on ART, emphasizing the need for tailored treatment strategies to combat drug resistance and improve management outcomes. In addition to HIV eradication efforts, understanding the dissemination of the oral microbiota in the body has emerged as a crucial aspect of overall health. Dysbiosis of the oral microbiome has been linked to systemic diseases such as cardiovascular diseases, cancers, and respiratory illnesses. Studies highlight the intricate interplay between oral health and well-being, advocating for interdisciplinary approaches in healthcare. Overall, while significant strides have been made towards HIV eradication and understanding the systemic implications of oral health, continued research efforts and interdisciplinary collaboration are essential to address the evolving challenges and improve long-term health outcomes for PLHIV.