Electric fields depending on tension render on biosystem as the activating and inhibiting influence. In article the effects found in cages and microbes’ communities which arise under the influence of electrostatic field, tension of 4 - 20 kV/m and the fixed time spent of cages in the field within 30 seconds which the period without influence of the field within 2 hours followed are described. The electrostatic block has been installed out of the bioreactor. Microbes mix continuously circulated between the bioreactor and the external block with electrostatic processing. All cycles of tests of advanced production were compared to control system (without electrostatic processing). At recirculation of 50% and the fixed parameter of the physical field depending on a cellular mycelium received acceleration of oxidation of an intracellular substratum to 40% in comparison with oxidation in control system. On the basis of the received experimental results it is offered to use electrostatic fields for acceleration of the second stage of biosynthesis of antibiotics, for optimization of processes of oxidation of organic pollution in bioreactors at biochemical sewage treatment.