Headache is the most frequent symptom in patients with cerebral venous thrombosis. However, patients presenting with solely headache in cerebral venous thrombosis are uncommon. We report a patient who is a smoker, presented with headache and a history of dehydration secondary to gastroenteritis. Magnetic resonance venogram of brain showed thrombosis of the left transverse, sigmoid sinus. Patient was treated with heparin and warfarin and improved on treatment. So in smokers with newer onset of headache and with history of dehydration, cerebral venous sinus thrombosis should be considered as a possible diagnosis.