A hepatitis B virus (HBV) is endemic in India and has an etiological role in hepatitis, 50-60% of which end up with chronic liver disease. A total of 100 patients diagnosed as alcoholic liver cirrhosis were screened for HBV. 100 healthy subjects without any evidence of chronic liver disease were taken as controls. 18% of the samples were positive for hepatitis B surface antigen (HBsAg). Serum bilirubins, enzymes (AST, ALT, ALP, and GGT) were significantly increased. In conclusion, heavy alcohol consumption significantly increases liver disease with HBV positive patients.