The prosperity of a nation depends on the development of nation’s economy, when more people come forward to start their own business the economy will get improved. So inculcating entrepreneurial knowledge among students will improve the employment status in the country. The study was conducted to assess the motivating factors for taking up entrepreneurship among college students. For the present study, 150 girl students residing in Chennai city were selected by purposive sampling method. Questionnaire was administered to collect the data from the students. The aim of the present study was to identify the motivational factor, their family background in entrepreneurship and their attitude towards entrepreneurship. Many students were willing to take up entrepreneurship as their career after their graduation because of many motivating factors like flexibility in working hours and probability to become an employer.