Platelet concentrates (PC), also known as platelet gel or plasma rich in growth factors is supra-physiological concentrate of platelet in plasma, derived from autologous blood after its centrifugation. It has dynamic use in regenerative and repair therapy. It gained popularity in late 1970s in Europe, wherein fibrin sealants were used for haemostasis and tissue closure. Subsequently it evolved into platelet rich plasma (1st generation PC) and platelet rich fibrin (2nd generation PC).Common to both the generations are presence of multiple growth factors which has potential to catalyse soft and hard tissue healing. It has been used in field of medicine and dentistry in varied forms. This paper aims to review various applications of PC, specifically in field of Oral and Maxillofacial Surgery.