Antibacterial activity of leaf extracts of some herbs against some clinical isolates

The antibacterial activity of leaf extract of Chrozophora rottleri, Oxalis corniculata, Parthenium hysterophorus and Solanium xanthocarpum were evaluated in-vitro against some clinical isolates by agar-well diffusion method. Two solvents chloroform and methanol were used for extraction of bioactive compound from fresh leaves. Antimicrobial potential of leaf extract was determined by measuring the zone of inhibition. It was concluded from the results that both chloroform as well as methanol extracts of leaf of tested herbs were quite effective in inhibiting the growth of clinical isolates. Result also revealed that methanol extract has more antibacterial potential than chloroform extract. Methanol extract of Chrozophora rottleri and Oxalis corniculata has very good antibacterial potential against all the clinical isolate. Therefore, the leaf extracts of this plant can be selected for further investigation to determine their therapeutic potential.